세균 세포벽 합성 기전
그람음성균의 cell envelope 합성 기전 및 온전성 유지 기전
항생제 내성 및 퍼시스턴스 기전
학력
2000-2007: 박사, 코넬대학교 미생물학과, 이타카, 뉴욕
1994-1999: 석사, 서울대학교 미생물학과, 서울
1990-1994: 학사, 서울대학교 미생물학과, 서울
약력/경력
2018-현재: 조교수, 성균관대학교 생명과학과
2007-2018: 박사 후 연구원, 하버드대 의대
학술지 논문
(2023)
Assembly of Bacterial Surface Glycopolymers as an Antibiotic Target.
JOURNAL OF MICROBIOLOGY.
61,
3
(2022)
Structural basis of flagellar motility regulation by the MogR repressor and the GmaR antirepressor in Listeria monocytogenes.
NUCLEIC ACIDS RESEARCH.
50,
19
(2022)
Structural analysis of the virulence gene protein IceA2 from Helicobacter.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS.
612,
(2022)
The Tol-Pal System Plays an Important Role in Maintaining Cell Integrity During Elongation in Escherichia coli.
FRONTIERS IN MICROBIOLOGY.
13,
-
(2022)
Comparative analysis of the Colistin resistance-regulating gene cluster in Klebsiella species.
JOURNAL OF MICROBIOLOGY.
60,
5
(2022)
A Cell Wall Hydrolase MepH Is Negatively Regulated by Proteolysis Involving Prc and NlpI in Escherichia coli.
FRONTIERS IN MICROBIOLOGY.
13,
-
(2021)
Transposon insertion site sequencing (TIS) of Pseudomonas aeruginosa.
JOURNAL OF MICROBIOLOGY.
59,
12
(2019)
Construction of a multicopy genomic DNA library and its application for suppression analysis.
JOURNAL OF MICROBIOLOGY.
57,
12
(2019)
Pathway-Directed Screen for Inhibitors of the Bacterial Cell Elongation Machinery.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY.
63,
1
(2018)
A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery.
PLOS GENETICS.
14,
10
(2017)
A viral protein antibiotic inhibits lipid II flippase activity.
NATURE MICROBIOLOGY.
2,
11
(2017)
The mecillinam resistome reveals a role for peptidoglycan endopeptidases in stimulating cell wall synthesis in Escherichia coli.
PLOS GENETICS.
13,
7
(2016)
Bacterial cell wall biogenesis is mediated by SEDS and PBP polymerase families functioning semi-autonomously.
NATURE MICROBIOLOGY.
1,
10
(2016)
Identification of MltG as a potential terminase for peptidoglycan polymerization in bacteria.
MOLECULAR MICROBIOLOGY.
99,
4
(2015)
The Role of Cytoskeletal Elements in Shaping Bacterial Cells.
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY.
25,
3
(2014)
Beta-Lactam Antibiotics Induce a Lethal Malfunctioning of the Bacterial Cell Wall Synthesis Machinery.
CELL.
159,
6
(2013)
Identification of the SlmA Active Site Responsible for Blocking Bacterial Cytokinetic Ring Assembly over the Chromosome.
PLOS GENETICS.
9,
2
(2011)
Nucleoid occlusion factor SlmA is a DNA-activated FtsZ polymerization antagonist.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA.
108,
9
(2009)
Identification of amino acid residues of the pheromone-binding domain of the transcription factor TraR that are required for positive control.
MOLECULAR MICROBIOLOGY.
73,
3
(2009)
Transsexuality in the Rhizosphere: Quorum Sensing Reversibly Converts Agrobacterium tumefaciens from Phenotypically Female to Male.
JOURNAL OF BACTERIOLOGY.
191,
10
